Dog breeding is regulated in the United States, but the regulations vary by state. Some states have laws and regulations governing dogs' breeding and sale, while others have no specific rules in place.

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At the federal level, the United States Department of Agriculture (USDA) is responsible for enforcing the Animal Welfare Act (AWA), which sets standards for treating animals in commercial breeding facilities. These facilities, known as "Class A" breeders, are subject to inspections by the USDA to ensure they comply with the AWA. However, this law only applies to breeders who sell their dogs to pet stores or research facilities, and many breeders who sell directly to the public are not covered.

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The United States also has many organizations that promote responsible breeding practices, such as the American Kennel Club (AKC) and the United Kennel Club (UKC). Still, these organizations are not government agencies, and their rules and regulations are not legally binding.

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Most of the regulation is left to the state and local level; some states require commercial dog breeders to be licensed and inspected, others prohibit puppies' sale in pet stores, and others have no specific laws related to dog breeding.

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Dog breeding is regulated in the United States, but the regulations vary by state. They often do not fully cover all the aspects of breeding, like the welfare and genetic health of the breeding dogs, and many breeders are not subject to inspection. Therefore, it is essential for potential dog owners to research and carefully choose a responsible and reputable breeder.